GAP JUNCTIONS IN ARTERIAL ENDOTHELIUM
نویسندگان
چکیده
منابع مشابه
Gap Junctions in Arterial Endothelium
Tight junctions are well characterized membrane specializations in vascular endothelium . These structures seal the interspace between adjacent endothelial cells, either completely, as in cerebral vessels (10), or incompletely, as in striated and cardiac muscle capillaries (8, 19) as well as in noncerebral arteries (4, 5) . Gap junctions in vascular endothelium have not been described in the li...
متن کاملIndividual gap junction plaques contain multiple connexins in arterial endothelium.
Gap-junctional intercellular communication in endothelial cells is implicated in the coordination of growth, migration, and vasomotor responses. Up to 3 connexin types, connexin40 (Cx40), Cx37, and Cx43 may be expressed in vascular endothelium according to vascular site, species, and physiological conditions. To establish how these connexins are organized at the level of the individual endothel...
متن کاملMultiple connexin expression in regenerating arterial endothelial gap junctions.
Endothelial cells form gap junctions that, according to vessel type, may be composed of up to 3 types of connexin, connexin37, connexin40, and connexin43. Although changes in connexin expression have been linked to growth and injury in cultured endothelial cells, information on connexin expression in regenerating endothelium in situ is lacking. We investigated gap junction distribution and expr...
متن کاملGap Junctions
Gap junctions are sites of intercellular communication where cells are interconnected by small aqueous channels (Figure 1b). The term is morphological, for in transmission electron micrographs of thin sections, the unit membranes of the joined cells are seen to remain separated by a gap of about 2 nm (Figure 1a, inset). The gap of gap junctions distinguishes them from tight junctions, or zonula...
متن کاملGap junctions in development.
Almost since their discovery gap junctions have attracted attention as possible means by which cell growth and cell development could be controlled since they provide for direct cell-cell communication (Potter et al, 1966; Loewenstein, 1968; Sheridan, 1968; Crick, 1970; Bennett, 1973). A corollary, of course, is that gap junctions play an important role in embryogenesis. This idea is made espec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1973
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.57.1.247